AZITHROMYCIN-MEDICINES ABOUT CHEMICAL FORMULA, USES, MECHANISM, RECOMMENDED DOSAGE OF, ADVISE, AVAILABILITY, SIDE EFFECT, DRUG INTERACTION, MARKETED WITH OTHER DRUGS, EXAMPLES.

AZITHROMYCIN



CHEMICAL FORMULA:C38H72N2O12

 

USES:

used to treat many bacterial infections like

respiratory tract infections

throat  infection

skin infections

ear infections

eye infections

sexually transmitted diseases

Many other bacterial infections.

(In , a small study was  investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug hydroxychloroquine. The results were positive but not officially declared treatment guideline.)

 

MECHANISM:

Category - macrolide-type antibiotic.

works by stopping the growth of bacteria.


for bacterial growth, bacteria require protein synthesis.Azithromycin binds to the 23S rRNA of the bacterial 50S ribosomal subunit and stops bacterial protein synthesis process. That results we can control various bacterial infections.

 

Bacteria like:

Haemophilus influenza

Moraxella catarrhalis 

Streptococcus pneumonia

Chlamydophila pneumonia

Streptococcus pneumonia

Chlamydia trachomatis 

Neisseria gonorrhoeae.

 

RECOMMENDED DOSAGE OF:

(This is ideal dose for your knowledge.Do not take without consult your DOCTOR or PHARMACIST)

 

Adult dosage:

take 500 mg/day for 3 days.

 

Child dosage:

take 10 mg/kg of body weight for 3 days.

 

ADVISE:

SCHEDULE H PRESCRIPTION DRUG-mean- Not to be sold by retail without the prescription of a Registered Medical Practitioner.

Tell your doctor and pharmacist if you are allergic to azithromycin.

Azithromycin passes into brest milk. Consult your doctor before breast-feeding.

Absorption of azithromycin decreased by antacids containing al or mg . So if you take an antacid, wait 2 hr before or after taking azithromycin.

Liver disease

Kidney disease

Myasthenia gravis

A heart rhythm disorder

Low levels of potassium in your blood

 

AVAILABILITY:

Tablet

Syrup

 

SIDE EFFECT OF :

Nausea

Diarrhea

Vomiting

Stomach pain

Headache

 

DRUG INTERACTION WITH:

 

Drugs that can cause QT prolongation like selegiline, amitriptyline, nortriptyline

Anticoagulants: warfarin

Antacids containing aluminum or magnesium

Carbamazepine

Digoxin

Corticosteroids :hydrocortisone, methylprednisolone

Nelfinavir

Phenytoin

Fepristone

NSAIDS: ibuprofen, diclofenac, naproxen

Quinidine

 

MARKETED WITH OTHER DRUGS:

 

Cefixime+ Azithromycin

Azithromycin + Fluconazole + Secnidazole

Azithromycin +  Ambroxol

Azithromycin + Fluconazole + Ornidazole

Cefpodoxime  + Azithromycin








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