CHEMICAL FORMULA:C38H72N2O12
USES:
used to treat many bacterial infections like
respiratory tract infections
throat infection
skin infections
ear infections
eye infections
sexually transmitted diseases
Many other bacterial infections.
(In , a small study
was investigate the treatment of
COVID-19 with a combination of azithromycin and the anti-malaria drug hydroxychloroquine.
The results were positive but not officially declared treatment guideline.)
MECHANISM:
Category
- macrolide-type antibiotic.
works
by stopping the growth of bacteria.
for bacterial growth, bacteria require protein synthesis.Azithromycin
binds to the 23S rRNA of the bacterial 50S ribosomal subunit and stops
bacterial protein synthesis process. That results we can control various
bacterial infections.
Bacteria like:
Haemophilus influenza
Moraxella catarrhalis
Streptococcus pneumonia
Chlamydophila pneumonia
Streptococcus pneumonia
Chlamydia trachomatis
Neisseria gonorrhoeae.
RECOMMENDED DOSAGE OF:
(This is ideal dose for your knowledge.Do not
take without consult your DOCTOR or PHARMACIST)
Adult dosage:
take 500 mg/day
for 3 days.
Child dosage:
take 10 mg/kg
of body weight for 3 days.
ADVISE:
SCHEDULE H PRESCRIPTION DRUG-mean-
Not to be sold by retail without the prescription of a Registered Medical
Practitioner.
Tell
your doctor and pharmacist if you are allergic to azithromycin.
Azithromycin
passes into brest milk. Consult your doctor before breast-feeding.
Absorption
of azithromycin decreased by antacids containing al or mg . So if you take an antacid, wait 2
hr before or after taking azithromycin.
Liver disease
Kidney disease
Myasthenia gravis
A heart rhythm disorder
Low levels of potassium in your blood
AVAILABILITY:
Tablet
Syrup
SIDE EFFECT OF :
Nausea
Diarrhea
Vomiting
Stomach
pain
Headache
DRUG INTERACTION WITH:
Drugs
that can cause QT prolongation like selegiline, amitriptyline, nortriptyline
Anticoagulants: warfarin
Antacids containing
aluminum or magnesium
Carbamazepine
Corticosteroids
:hydrocortisone, methylprednisolone
Nelfinavir
Phenytoin
Fepristone
NSAIDS:
ibuprofen, diclofenac, naproxen
Quinidine
MARKETED WITH OTHER DRUGS:
Cefixime+ Azithromycin
Azithromycin + Fluconazole + Secnidazole
Azithromycin + Ambroxol
Azithromycin + Fluconazole + Ornidazole
Cefpodoxime + Azithromycin
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