PARACETAMOL-MEDICINES ABOUT CHEMICAL FORMULA, USES, MECHANISM, RECOMMENDED DOSAGE OF, ADVISE, AVAILABILITY, SIDE EFFECT, DRUG INTERACTION, MARKETED WITH OTHER DRUGS, EXAMPLES.

 

Paracetamol

PARACETAMOL
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Every one knows about pcm,right?good.but no one knows how the pcm works.


CHEMICAL FORMULA: C8H9NO2

Commonly called : PCM

Alternate Name: Acetaminophen


MECHANISM OF ACTION:

PARACTEMAOL belongs to a class of drugs called analgesics ( reduce pain ) and antipyretics (reduce fever). The exact mechanism of action of paracetamol is not known. It may selectively inhibit COX(cyclooxygenase enzyme) activities in the brain, which may contribute to its ability to treat fever and pain.


Uses:

Mainly used reduce fever and pain like

headache
menstrul periods
back pain
Osteoarthritis
Cold & Flu
Headache
Fever And Cold
Muscle Ache
Arthritis
Backache
Toothache

 

 

Paracetamol is commonly prescribed to relieve pain and fever.

 

 

 

 

Recommended dosage of paracetamol.

·       For ADULT:  1 gram (1000 mg) per dose, 4 gram (4000 mg) per day

 

·       For Children: 10-15 mg per kg of body weight. this dose can be given for             every 4-6 hours and maximum 4 times a day

 do not give paracetamol to child below 2 months.

       It is dangerous to take this medication more than recommended dosage.

 

ADVISE:

  More use of Paracetamol leads to serious injury to your liver.

While taking paracetamol consult your doctor if you are alcohol addicted. 

Alcohol with paracetamol cause alcoholic liver diseases faster than only alcohol does.


Without consulting your doctor or pharmacist do not take any medicines. 

A Person who is taking more and more  of this drugs.avoid use if paracetamol.

N-acerylcystein may be prescribed for primary treatment of paracetamol overdose.This antidote will be effective within 24 hr.


AVAILABILITY:


tablet
Syrup 
suspension 
capsule 
injactable  
SIDE EFFECT OF PARACETAMOL

Nausea Vomiting
Loss of appetite
stomach pain
If you found any of these symptoms after having paracetamol, consult your doctor or pharmacist immediately

DRUG INTERACTION WITH PARACETAMOL

·      Alcohol (Ethanol)
·       Alcohol and Dextrose Injection USP
·       Amyl Nitrate / Sodium Nitrate
·       Leflunomide
·        Prelocaine
·        Lidocaine Topical
·        Some Anti-Convulsant drugs (Amobarbital , Butalbital, Pantobarbitol, Phenobarbital, Secobarbital, Carbamazepine )
·       Non Narcotic Analgesic ( Diflunisal)
·       A typical Anti-Tuberculosis drug(Isoniazid)
·        Warfarin 


PARACETAMOL MARKETED WITH OTHER DRUGS
·       Paracetamol + Diclofenac Sodium + Serratiopeptidase Paracetamol + Aceclofenac
 paracetamol +ibuprofen 
paracetamol +nimesulide
·       Paracetamol + Dicyclomine Hydrochloride
·       Paracetamol + Mefenamic Acid  
·       Paracetamol + Caffeine
·       Paracetamol + Aceclofenac + Tizanidine
·       Paracetamol + Domperidone
·       Paracetamol + Promethazine
·       Paracetamol + Diclofenac Sodium
·       Paracetamol + Tramadol
·       Paracetamol + Cetrizine + Phenylpropanolamine
·       Paracetamol + Diclofenac Potassium + Serratiopeptidase + Magnesium Trisilicate
·       Paracetamol + Diclofenac Potassium + Chlorzoxazone
·       Paracetamol + Chlorpheniramine Maleate + Phenyleprine
·       Paracetamol + Tramadol + Domperidone
·       Paracetamol + Ibuprofen + Serratiopeptidase







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