ATORVASTATIN
ATORVASTATIN CHEMICAL FORMULA : C33H35FN2O5
ATORVASTATIN USES :
used to treat high
cholesterol
(high LDL
cholesterol are increased risk of
developing cardiovascular disease.)
So also used preventive agent like
Myocardial infarction
Stroke
Angina
reduce the risk of
cardiovascular disease
ATORVASTATIN MECHANISM OF ACTION :
Class :statin
Atorvastatin is a
lipid-lowering drug.
Atorvastatin is
inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase.
Atorvastatin inhibit
the conversion of HMG-CoA to mevalonic acid. This conversion is important in lipid metabolism .
LDL - low-density
lipoprotein (bad cholesterol)
VLDL - very-low-density
lipoprotein
HDL - high density lipoprotein (good cholesterol)
increase HDL is
good for health
increase LDL is
bad for health
Atorvastatin acts
in the liver, where decreased hepatic cholesterol concentrations and stimulate increases hepatic uptake of LDL.
Atorvastatin also
reduces
Very-Low-Density
Lipoprotein-Cholesterol (VLDL-C)
serum
triglycerides (TG)
Intermediate
Density Lipoproteins (IDL)
ATORVASTATIN RECOMMENDED DOSAGE :
(This is ideal dose for your knowledge.Do not take
without consult your DOCTOR or PHARMACIST)
As per body weight & condition
ATORVASTATIN ADVISE:
SCHEDULE H PRESCRIPTION DRUG-mean- Not
to be sold by retail without the prescription of a Registered Medical Practitioner.
Do not take Atorvastatin if you are pregnant,
planning a pregnancy or breastfeeding.
If you have type 2 diabetes, your
doctor may advise monitoring your blood sugar levels because Atorvastatin can raise your blood
sugar a little.
Tell your
doctor if you have ever had:
Liver problems
Kidney disease
Diabetes
Thyroid
disorder
ATORVASTATIN AVAILABILITY :
TABLET
ATORVASTATIN 10
ATORVASTATIN 20
ATORVASTATIN 40
ATORVASTATIN SIDE EFFECT :
Nausea
Vomiting
Headache
Constipation
High glucose level in blood
Muscle pain
ATORVASTATIN DRUG INTERACTION :
Itraconazole
Ketoconazole
Cimetidine
Clarithromycin
Colchicine
Digoxin
Diltiazem
Erythromycin
Rifampin
ATORVASTATIN MARKETED WITH OTHER DRUGS:
Atorvastatin Calcium + Fenofibrate + Folic acid
Atorvastatin Calcium +Ezetimibe
Atorvastatin Calcium +Telmisartan
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