FLUCONAZOLE
CHEMICAL FORMULA: C13H12F2N6O
USES:
Fluconazole used
to treat fungal infections like
Vaginal
fungal infection
Fungal
infection in mouth, throat, esophagus , abdomen , lungs, blood. other organs.
fungal
infections of the eye, skin and nails.
Fluconazole
is used to prevent fungal infection in people who have a weak immune system
caused by cancer treatment, bone marrow transplant, treatment of AIDS.
MECHANISM:
Fluconazole is an azole
class antifungal medicine.
Fluconazole is a lanosterol 14-α-demethylase enzyme inhibitor.
lanosterol 14-α-demethylase
enzyme works to convert lanosterol to ergosterol in fungus. which is necessary for fungal cell
wall synthesis.
By 14-α-demethylase enzyme
inhibition fluconazole interrupt conversion of lanosterol to
ergosterol and disrupt of fungal membranes.which inhibit fungal growth.
RECOMMENDED DOSAGE OF:
(This is ideal dose for your knowledge. Do
not take without consult your DOCTOR or PHARMACIST)
fluconazile dose for adults:
150 mg orally as a single dose
Fluconzole dose for children: (6 months to 12
years)
3 mg/kg orally as a single dose
ADVISE:
SCHEDULE H PRESCRIPTION DRUG-mean-
Not to be sold by retail without the prescription of a Registered Medical
Practitioner.
Tell your
doctor if you have ever had any allergic reaction to fluconazole class
medicines.
Fluconazole in pregnancy:
Pregnant, trying for a baby or breastfeeding woman consult with doctor.
Tell
your doctor if you have or have ever had cancer,acquired immunodeficiency
syndrome, irregular heartbeat, kidney or liver disease.
AVAILABILITY:
Tablet 50/100/200 mg
SIDE EFFECT OF :
Nausea
vomiting
Dizziness
stomach pain
heartburn
DRUG INTERACTION WITH:
Alfuzosin
Amiodarone
Aripiprazole
Atazanavir
Bedaquiline
Citalopram
Clarithromycin
Clozapine
Domperidone
Donepezil
Erythromycin
Granisetron
Haloperidol
Iloperidone
Itraconazole
Ketoconazole
Levomethadyl
Lomitapide
Methadone
Ondansetron
Quetiapine
Quinidine
Sparfloxacin
Thioridazine
Voriconazole
MARKETED WITH OTHER DRUGS:
Fluconazole + Azithromycin + Ornidazole
Fluconazole + Azithromycin + Secnidazole
Fluconazole + Tinidazole
Where you find MEDICINES ABOUT,CHEMICAL FORMULA,USES,MECHANISM,RECOMMENDED DOSAGE OF,ADVISE,AVAILABILITY,SIDE EFFECT,DRUG INTERACTION,MARKETED WITH OTHER DRUGS,EXAMPLES.
ConversionConversion EmoticonEmoticon