DOMPERIDONE
Chemical Formula:
C22H24CLN5O2
Domperidone Uses:
treatment of
Indigestion
Nausea
Vomiting
Dosage :
· for gastrointestinal motility disorders:
Adults—10 mg three to four times daily.
· Nausea and vomiting:
Adults—20 mg three to four times daily.
Mechanism:
Dopamine receptor blocking properties and shows Antiemetic properties. Mainly blocks D2 and D3 dopamine receptors, which are regulates nausea and vomiting.
increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.
ADVISE:
Domperidone is not an over the counter (OTC) medicine and it is not advisable to take it without a prescription or medical supervision.
DRUG AVAILIBILITY:
TABLET
SYRUP
DROP
SIDE EFFECT OF DOMPERIDONE:
Headache
Dryness in mouth
Stomach pain
Diarrhea
DRUG INTERACTION WITH DOMPERIDONE
Using domperidone with any of the following medicines is not recommended.
Amisulpride
Bepridil
Cisapride
Darunavir
Dronedarone
Fluconazole
Ketoconazole
Mesoridazine
Pimozide
Piperaquine
Posaconazole
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone
DOMPERIDONE MARKETED WITH OTHER DRUGS
Domperidone + Omeprazole
Lansoprazole +Domperidone
Domperidone + Rabeprazole
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